publications

2025

  1. Metabolomics
    Molecular Networking Reveals Antioxidant Properties and Phenolic Profiles of Four Rosaceae Seeds
    M. J. Lim, J. Park, M. S. Lee, and 4 more authors
    Plants, 2025
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  2. Proteomics
    A Shrinkage-based statistical method for testing group mean differences in quantitative bottom-up proteomics
    N. Lee, H. Yoo, J. Kim, and 1 more author
    BMC Bioinformatics, 2025
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  3. Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis
    J. H. Song, S. H. Mun, S. Mishra, and 12 more authors
    Biomolecules & Therapeutics, 2025
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  4. AI/ML & VS
    Discovery of natural RORγt inhibitor using machine learning, virtual screening, and in vivo validation
    H. Yoo, S. J. Han, J. E. Lee, and 15 more authors
    BMC Bioinformatics, 2025
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  5. Metabolomics
    Ex Vivo Interaction Between Human Gut Microbiota and Artemisinin: A Multi-Omics Perspective
    P. W. P. Gomes, H. Mannochio-Russo, S. N. Lablokov, and 5 more authors
    ACS Omega, 2025
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  6. Metabolomics
    Mass Spectral Data of Primary and Secondary Metabolites Changes in Medicinal Plants by Solvent Polarity
    J. Park, J. Lee, C. Cho, and 5 more authors
    Scientific Data, 2025
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  7. Metabolomics
    1H-NMR and molecular networking-guided dereplication of phloroglucinol meroterpenoids from Cleistocalyx operculatus buds as neuraminidase inhibitors
    V. H. Mai, S. Choi, J. E. Ponce-Zea, and 5 more authors
    Phytochemistry, 2025
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  8. Cyclodepsipeptides and Fatty Acid Lactones from the Freshwater-Derived Fungus, Talaromyces gwangjuensis, and Their Potential as Autophagy Activators
    V. H. Mai and others
    Journal of Natural Products, 2025
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2024

  1. Bioinformatics
    plantMASST - Community-driven chemotaxonomic digitization of plants
    P. W. P. Gomes, others, H. Yang, and 2 more authors
    bioRxiv, 2024
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  2. Metabolomics
    Identification of novel dimers and chemical profiling of acid amide alkaloids in Piper nigrum
    Y. Jung, S. Y. Choi, J. W. Choi, and 5 more authors
    Food Chemistry, 2024
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  3. Panaxydol extracted from Panax ginseng inhibits NLRP3 inflammasome activation to ameliorate NASH-induced liver injury
    M. Y. Kim, B. Jeong, G. S. Lee, and 4 more authors
    International Immunopharmacology, 2024
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  4. Activation of Nuclear Factor Erythroid 2-Related Factor-2 by Oxylipin from Mangifera indica Leaves
    A. A. K. Khalil, M. Woo, D. Kang, and 4 more authors
    Antioxidants, 2024
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  5. A New Chromone from Angelica polymorpha Leaves
    D. Y. Jeong, T. K. Kim, Heejung Yang, and 3 more authors
    Chemistry of Natural Compounds, 2024
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  6. A New Chromone from Angelica dahurica
    N. Y. Kim, Heejung Yang, M. J. Kim, and 2 more authors
    Chemistry of Natural Compounds, 2024
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2023

  1. A New Chromone from Ostericum koreanum
    H. J. Lee, Y. J. Lee, S. G. Choi, and 6 more authors
    Chemistry of Natural Compounds, 2023
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  2. Antiviral Mechanisms of Saucerneol from Saururus chinensis against Enterovirus A71, Coxsackievirus A16, and Coxsackievirus B3
    J. H. Song, S. H. Mun, H. Yang, and 3 more authors
    Viruses, 2023
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  3. Metabolomics & Bioinformatics
    Open access repository-scale propagated nearest neighbor suspect spectral library for untargeted metabolomics
    W. Bittremieux, others, H. Yang, and 2 more authors
    Nature Communications, 2023
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  4. Triterpenoid saponins from Camellia sinensis roots with cytotoxic and immunomodulatory effects
    J. Lee, J. H. Lim, G. Y. Jung, and 6 more authors
    Phytochemistry, 2023
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  5. Metabolomics
    Simple identification of discriminative markers for four Citrus species using a combination of molecular networking and multivariate analysis
    Seong Yeon Choi, Birang Jeong, E. Mok, and 2 more authors
    Journal of Food Composition and Analysis, 2023
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2022

  1. New Pregnane Glycosides Isolated from Stapelia gigantea
    Hyeon Seok Jang, Seong Yeon Choi, Birang Jeong, and 3 more authors
    Chemistry of Natural Compounds, 2022
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  2. Metabolomics
    Mass spectrometry data on specialized metabolome of medicinal plants used in East Asian traditional medicine
    K. B. Kang, E. Jeong, S. Son, and 6 more authors
    Scientific Data, 2022
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  3. A New Chromone from Angelica polymorpha
    Y. Kwon, Heejung Yang, W. Chun, and 2 more authors
    Chemistry of Natural Compounds, 2022
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  4. Camellia japonica Root Extract Increases Antioxidant Genes by Induction of NRF2 in HeLa Cells
    J. H. Kim, Heejung Yang, and K. K. Kim
    Plants, 2022
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  5. Bioinformatics
    Hierarchical network analysis of co-occurring bioentities in literature
    Heejung Yang, N. Lee, B. Park, and 4 more authors
    Scientific Reports, 2022
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2021

  1. Metabolomics
    Investigation of Chemical Profiles of Different Parts of Morus alba using a Combination of Molecular Networking Methods with Mass Spectral Data from Two Ionization Modes of LC/MS
    S. Y. Choi, J. Park, J. Kim, and 2 more authors
    Plants, 2021
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  2. Two New Pterocarpans from Lespedeza tomentosa
    Y. Kwon, Heejung Yang, W. Chun, and 2 more authors
    Chemistry of Natural Compounds, 2021
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  3. arXiv
    A surrogate loss function for optimization of F_βscore in binary classification with imbalanced data
    N. Lee, Heejung Yang, and H. Yoo
    arXiv, 2021
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  4. α-Glucosidic hydroquinone derivatives from Viburnum erosum
    J. Park, J. Lee, H. S. Jang, and 5 more authors
    Phytochemistry, 2021
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  5. Bioinformatics
    Cluster Analysis of Medicinal Plants and Targets Based on Multipartite Network
    N. Lee, H. Yoo, and Heejung Yang
    Biomolecules, 2021
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  6. Lysosomal SLC46A3 modulates hepatic cytosolic copper homeostasis
    J. H. Kim, T. Matsubara, J. Lee, and 10 more authors
    Nature Communications, 2021
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2020

  1. Simultaneous Determination of two Diterpenoids, Continentalic Acid and Kaurenoic Acid, in the Water extract of Aralia continentalis and their Wound-Healing Activity
    G. Yoo, T. H. Lee, J. H. Lee, and 5 more authors
    Pharmacognosy Magazine, 2020
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  2. Metabolomics
    Feature-based molecular networking in the GNPS analysis environment
    L. F. Nothias, D. Petras, R. Schmid, and 59 more authors
    Nature Methods, 2020
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  3. Metabolomics
    Targeted Isolation of Cytotoxic Sesquiterpene lactones from Eupatorium fortunei by the NMR annotation tool, SMART 2.0
    J. Lee, J. Park, J. Kim, and 4 more authors
    ACS Omega, 2020
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  4. Metabolomics
    The Rapid Discrimination and Quality Assessment of Three Zanthoxylum species using 1H NMR Spectrometry
    H. S. Jang, B. R. Jeong, S. Y. Choi, and 3 more authors
    International Journal of Analytical Chemistry, 2020
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  5. Morin Hydrate Inhibits Influenza Virus entry into Host Cells and Has Anti-inflammatory Effect in Influenza-infected Mice
    E. H. Hong, J. H. Song, S. R. Kim, and 9 more authors
    Immune Network, 2020
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  6. Metabolomics
    Targeted Isolation of Lignans from Trachelospermum asiaticum Using Molecular Networking and Hierarchical Clustering Analysis
    J. Lee, H. S. Yang, H. Jeong, and 2 more authors
    Biomolecules, 2020
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2019

  1. Metabolomics
    Exploring novel secondary metabolites from natural products using pre-processed mass spectral data
    H. W. Kim, S. Y. Choi, H. S. Jang, and 3 more authors
    Scientific Reports, 2019
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  2. Comparative transcriptome analysis reveals higher expression of stress and defense responsive genes in dwarf soybeans obtained from the crossing of G. max and G. soja
    Y. W. Ban, N. S. Roy, Heejung Yang, and 7 more authors
    Genes & Genomics, 2019
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  3. Obovatol inhibits NLRP3, AIM2, and non-canonical inflammasome activation
    J. Kim, H. Ahn, B. C. Han, and 9 more authors
    Phytomedicine, 2019
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  4. Metabolomics
    in silico Annotation of Discriminative Markers of Three Zanthoxylum species Using Molecular Network derived Annotation Propagation
    J. Lee, R. R. Silva, H. S. Jang, and 4 more authors
    Food Chemistry, 2019
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  5. Lignan Dimers from Forsythia viridissima Roots and Their Antiviral Effects
    J. Huh, J. H. Song, S. R. Kim, and 4 more authors
    Journal of Natural Products, 2019
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2018

  1. Nuclear Factor Erythroid 2-Related Factor 2 Activating Triterpenoidal Saponins from Camellia japonica Roots
    K. W. Ko, L. D. Wahyudi, Y. S. Kwon, and 2 more authors
    Journal of Natural Products, 2018
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  2. A new phenolic compound from Phedimus middendorffianus with antiproliferative activity
    J. Lee, S. Woo, S. H. Sung, and 1 more author
    Natural Product Research, 2018
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  3. Therapeutic Efficacies of Artemisia capillaris Extract Cream Formulation in Imiquimod-Induced Psoriasis Models
    S. Y. Lee, S. Nam, S. Kim, and 7 more authors
    Evidence-Based Complementary and Alternative Medicine, 2018
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  4. The polyherbal drug GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica inhibits hepatic steatosis and fibroinflammation in high-fat diet-induced obese mice
    J. H. Lim, H. Lee, J. Ahn, and 7 more authors
    Journal of Ethnopharmacology, 2018
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  5. Simultaneous Determination and Stability Test of Two Phthalic Anhydride Derivatives, Senkyunolide A and Z-Ligustilide, in the Water Extract of Cnidium Rhizome
    H. S. Jang, K. B. Kang, G. Yoo, and 9 more authors
    Bulletin of the Korean Chemical Society, 2018
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  6. Chemical Constituents of Branches and Barks of Juglans mandshurica
    H. S. Jang, S. Y. Choi, B. Jeong, and 3 more authors
    Chemistry of Natural Compounds, 2018
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  7. Amentoflavone-induced oxidative stress activates NF-E2-related factor 2 via the p38 MAP kinase-AKT pathway in human keratinocytes
    L. D. Wahyudi, J. Jeong, Heejung Yang, and 1 more author
    The International Journal of Biochemistry & Cell Biology, 2018
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  8. E-p-Methoxycinnamoyl-α-L-rhamnopyranosyl ester, a phenylpropanoid isolated from Scrophularia buergeriana, increases nuclear factor erythroid-derived 2-related factor 2 stability by inhibiting ubiquitination in human keratinocytes
    J. Jeong, L. Wahyudi, Y. S. Keum, and 2 more authors
    Molecules, 2018
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  9. Determination of Five Chemical Markers in DF formula, the herbal composition of Ephedra intermedia, Rheum palmatum and Lithospermum erythrorhizon, using High Performance Liquid Chromatography-Ultraviolet Detection
    B. Jeong, J. S. Roh, M. Yoon, and 5 more authors
    Pharmacognosy Magazine, 2018
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  10. Antiproliferation of keratinocytes and alleviation of psoriasis by the ethanol extract of Artemisia capillaris
    S. Y. Lee, S. Nam, I. K. Hong, and 3 more authors
    Phytotherapy Research, 2018
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  11. A New Dibenzofuran from the Barks of Sorbus commixta
    S. Y. Choi, B. Jeong, H. S. Jang, and 6 more authors
    Records of Natural Products, 2018
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  12. Gangjihwan, a polyherbal composition, inhibits fat accumulation through the modulation of lipogenic transcription factors SREBP1C, PPARγand C/EBPα
    J. Jang, Y. Jung, S. Chae, and 5 more authors
    Journal of Ethnopharmacology, 2018
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2017

  1. Metabolomics
    Conduritol F, the discriminant marker between C. wilfordii and C. auriculatum by 1H NMR spectroscopy
    H. S. Jang, B. Jeong, S. Y. Choi, and 4 more authors
    Microchemical Journal, 2017
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  2. Effect of Gangjihwan on hepatic steatosis and inflammation in high fat diet-fed mice
    J. S. Roh, H. Lee, J. Lim, and 5 more authors
    Journal of Ethnopharmacology, 2017
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  3. Anti-differentiation effect of B,D-seco limonoids of Swietenia mahogany
    Heejung Yang, M. Choi, D. Y. Lee, and 1 more author
    Pharmacognosy Magazine, 2017
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  4. Metabolomics
    Fast and Simple Discriminative Analysis of Anthocyanins-Containing Berries Using LC/MS Spectral Data
    Heejung Yang, H. W. Kim, Y. S. Kwon, and 2 more authors
    Phytochemical Analysis, 2017
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  5. Hydrolyzable tannins from the fruits of Terminalia chebula Retz and their α-glucosidase inhibitory activities
    D. Y. Lee, H. W. Kim, Heejung Yang, and 1 more author
    Phytochemistry, 2017
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  6. Cytotoxic activities of Naturally Occurred Oleanane-, Ursane-, and Lupane-type Triterpenes on HepG2 and AGS cells
    Heejung Yang, H. W. Kim, Y. C. Kim, and 1 more author
    Pharmacognosy Magazine, 2017
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  7. The effects of herbal composition Gambigyeongsinhwan (4) on hepatic steatosis and inflammation in Otsuka Long-Evans Tokushima fatty rats and HepG2 cells
    S. Yoon, J. Kim, H. Lee, and 5 more authors
    Journal of Ethnopharmacology, 2017
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  8. New polyhydroxytriterpenoid derivatives from fruits of Terminalia chebula Retz. and their α-glucosidase and α-amylase inhibitory activity
    D. Y. Lee, H. W. Kim, Heejung Yang, and 1 more author
    Bioorganic & Medicinal Chemistry Letters, 2017
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  9. Lignans from Opuntia ficus-indica seeds protect rat primary hepatocytes and HepG2 cells against ethanol-induced oxidative stress
    J. W. Kim, Heejung Yang, H. W. Kim, and 2 more authors
    Bioscience, Biotechnology, and Biochemistry, 2017
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2016

  1. Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cells
    S. Han, A. J. Jeong, Heejung Yang, and 8 more authors
    Journal of Natural Products, 2016
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2015

  1. Flavonoids isolated from Lespedeza cuneata G. Don and their inhibitory effects on nitric oxide production in lipopolysaccharide-stimulated BV-2 microglia cells
    G. Yoo, S. J. Park, T. H. Lee, and 5 more authors
    Pharmacognosy Magazine, 2015
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  2. The ethanolic extract of Juglans sinensis leaves and twigs attenuates CCl_4-induced hepatic oxidative stress in rats
    Heejung Yang, S. H. Sung, and Y. C. Kim
    Pharmacognosy Magazine, 2015
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  3. Anti-Influenza Activity of Betulinic Acid from Zizyphus jujuba on Influenza A/PR/8 Virus
    E. H. Hong, J. H. Song, K. B. Kang, and 3 more authors
    Biomolecules & Therapeutics, 2015
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  4. Metabolomics
    Identification of ginsenoside markers from dry purified extract of Panax ginseng by a dereplication approach and UPLC-QTOF/MS analysis
    Heejung Yang, D. Y. Lee, K. B. Kang, and 4 more authors
    Journal of Pharmaceutical and Biomedical Analysis, 2015
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  5. Stereoisomer-Specific Anticancer Activities of Ginsenoside Rg3 and Rh2 in HepG2 Cells: Disparity in Cytotoxicity and Autophagy-Inducing Effects Due to 20(S)-Epimers
    J. H. Cheong, H. Kim, M. J. Hong, and 8 more authors
    Biological and Pharmaceutical Bulletin, 2015
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  6. Hepatoprotective constituents of Firmiana simplex stem bark against ethanol insult to primary rat hepatocytes
    J. W. Kim, Heejung Yang, N. Cho, and 3 more authors
    Pharmacognosy Magazine, 2015
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2014

  1. Chemical constituents isolated from Disporum viridescens leaves and their inhibitory effect on nitric oxide production in BV2 microglial cells
    N. Cho, Heejung Yang, J. W. Kim, and 2 more authors
    Bioorganic & Medicinal Chemistry Letters, 2014
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  2. Nanocomplexes based on amphiphilic hyaluronic acid derivative and polyethylene glycol-lipid for ginsenoside rg3 delivery
    J. Y. Lee, Heejung Yang, I. S. Yoon, and 6 more authors
    Journal of Pharmaceutical Sciences, 2014
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  3. Complete ^1H and ^13C NMR spectral analysis of the pairs of 20(S) and 20(R)-ginsenosides
    Heejung Yang, E. Moon, M. Choi, and 4 more authors
    Journal of Ginseng Research, 2014
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  4. Metabolomics
    Simultaneous Determination of Five Active Compounds in Artemisia princeps and A. capillaris based on UPLC-DAD and Discrimination of Two Species with Multivariate Analysis
    Heejung Yang, D. Y. Lee, M. Jeon, and 2 more authors
    Archives of Pharmacal Research, 2014
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2013

  1. Neuroprotective Benzyl Benzoate Glycosides from Disporum viridescens Roots in HT22 Hippocampal Neuronal Cells
    N. Cho, Heejung Yang, M. Lee, and 4 more authors
    Journal of Natural Products, 2013
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  2. Salicortin-derivatives from Salix pseudo-lasiogyne twigs inhibit adipogenesis in 3T3-L1 cells via modulation of C/EBPαand SREBP1c dependent pathway
    M. Lee, S. H. Lee, J. Kang, and 5 more authors
    Molecules, 2013
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  3. Plant-derived juvenile hormone III analogues from the stem barks of Cananga latifolia
    Heejung Yang, H. S. Kim, E. J. Jeong, and 3 more authors
    Phytochemistry, 2013
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  4. Cognitive-enhancing effects of Rhus verniciflua bark extract and its active flavonoids with neuroprotective and anti-inflammatory activities
    N. Cho, K. Y. Lee, J. Huh, and 5 more authors
    Food and Chemical Toxicology, 2013
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  5. Neuroprotective compounds from twigs of Salix pseudo-lasiogyne and their anti-amnesic effects on scopolamine-induced memory deficit in mice
    Heejung Yang, S. Lee, S. H. Sung, and 2 more authors
    Planta Medica, 2013
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2012

  1. Metabolomics
    Implication of the stereoisomers of ginsenoside derivatives in anti-proliferative effect of HSC-T6 cells
    Heejung Yang, G. Yoo, H. S. Kim, and 4 more authors
    Journal of Agricultural and Food Chemistry, 2012
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  2. Stereochemical assignment of five new lignan glycosides from Viscum album by NMR study combined with CD spectroscopy
    N. X. Nhiem, H. Y. Lee, N. Y. Kim, and 5 more authors
    Magnetic Resonance in Chemistry, 2012
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  3. Neuroprotective and anti-inflammatory effects of flavonoids isolated from Rhus verniciflua in neuronal HT22 and microglial BV2 cell lines
    N. Cho, J. H. Choi, Heejung Yang, and 4 more authors
    Food and Chemical Toxicology, 2012
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  4. Cytotoxic terpenoids from Juglans sinensis leaves and twigs
    Heejung Yang, H. J. Cho, S. H. Sim, and 5 more authors
    Bioorganic & Medicinal Chemistry Letters, 2012
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  5. Anti-inflammatory phenolics isolated from Juniperus rigida leaves and twigs in lipopolysaccharide-stimulated RAW264.7 macrophage cells
    E. J. Jeong, H. Seo, Heejung Yang, and 3 more authors
    Journal of Enzyme Inhibition and Medicinal Chemistry, 2012
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  6. Neuroprotective iridoid glycosides from Cornus officinalis fruits against glutamate-induced toxicity in HT22 hippocampal cells
    E. J. Jeong, T. B. Kim, Heejung Yang, and 4 more authors
    Phytomedicine, 2012
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  7. Chemical constituents of Polygala tenuifolia roots and their inhibitory activity on lipopolysaccharide-induced nitric oxide production in BV2 microglia
    N. Cho, J. Huh, Heejung Yang, and 4 more authors
    Journal of Enzyme Inhibition and Medicinal Chemistry, 2012
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2011

  1. Inhibitory constituents of Euonymus alatus leaves and twigs on nitric oxide production in BV2 microglia cells
    E. J. Jeong, Heejung Yang, S. H. Kim, and 3 more authors
    Food and Chemical Toxicology, 2011
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  2. Antiproliferative triterpenes from the leaves and twigs of Juglans sinensis on HSC-T6 cells
    Heejung Yang, E. J. Jeong, J. Kim, and 2 more authors
    Journal of Natural Products, 2011
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  3. Neuroprotective diarylheptanoids from the leaves and twigs of Juglans sinensis against glutamate-induced toxicity in HT22 cells
    Heejung Yang, S. H. Sung, J. Kim, and 1 more author
    Planta Medica, 2011
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2010

  1. Triterpenoidal saponins of Pulsatilla koreana roots
    Heejung Yang, Y. W. Cho, S. H. Kim, and 2 more authors
    Phytochemistry, 2010
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